Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.60 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984953 | 1.00 | TBXAS1 (0.62) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL29187188 | 1.00 | TBXAS1 (0.62) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL27624949 | 1.00 | TBXAS1 (0.62) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL10981662 | 1.00 | TBXAS1 (0.62) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2002836 | 1.00 | TBXAS1 (0.62) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL10981660 | 1.00 | TBXAS1 (0.62) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL10984950 | 1.00 | TBXAS1 (0.62) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2302782 | 0.93 | CHRNB2 (0.64) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7520275 | 0.93 | CHRNB2 (0.64) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL6966605 | 0.93 | CHRNB2 (0.64) | TBXAS1CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960571-B2 | Silicon-based cross-coupling reagent and production method of organic compound using the same | KYOTO UNIVERSITY (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | KYOTO UNIVERSITY (JP) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | DNMT1, TET3, CTCF | TBXAS1 3207/4885CHRNB2 4162/4885CHRNA4 4060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.