Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850067 | 0.84 | RAB9A (0.62) | RAB9AMAPTHTTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28428173 | 0.82 | RAB9A (0.61) | RAB9AMAPTHTTALDH1A1TSHR | |
| SCHEMBL5928389 | 0.78 | MAPT (0.62) | RAB9AMAPTHTTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL30034113 | 0.77 | MAPT (0.60) | RAB9AMAPTHTTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28398239 | 0.77 | MAPT (0.60) | RAB9AMAPTHTTALDH1A1TSHR | |
| SCHEMBL7996781 | 0.76 | LMNA (0.57) | RAB9AMAPTHTTALDH1A1TSHR | |
| SCHEMBL12136194 | 0.76 | RAB9A (0.68) | RAB9AMAPTHTTALDH1A1TSHR | |
| SCHEMBL12135849 | 0.76 | SMN1; SMN2 (0.58) | RAB9AMAPTHTTALDH1A1TSHR | |
| SCHEMBL6204453 | 0.75 | RAB9A (0.62) | RAB9AMAPTHTTALDH1A1TSHR | |
| SCHEMBL9697949 | 0.75 | LMNA (0.54) | RAB9AMAPTHTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |