Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.77 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.77 |
| ▸ | HTR3B | O95264 | 3/20 | 0.77 |
| ▸ | HTR3A | P46098 | 3/20 | 0.77 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.77 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.77 |
| ▸ | USP2 | O75604 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | HTR6 | P50406 | 4/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylpiperazine SCHEMBL27922559 | 0.93 | ADRB1 (0.71) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Phenylpiperazine SCHEMBL11621472 | 0.92 | ADRB1 (0.83) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Phenylpiperazine SCHEMBL6495303 | 0.90 | SIGMAR1 (0.67) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Phenylpiperazine SCHEMBL29235064 | 0.90 | TSHR (0.69) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Phenylpiperazine SCHEMBL27606301 | 0.88 | ADRB1 (0.91) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Phenylpiperazine SCHEMBL29135595 | 0.88 | ADRB1 (1.00) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Phenylpiperazine SCHEMBL27858598 | 0.88 | ADRB1 (1.00) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Phenylpiperazine SCHEMBL55125 | 0.88 | ADRB1 (1.00) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Phenylpiperazine SCHEMBL24889 | 0.88 | ADRB1 (1.00) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Phenylpiperazine SCHEMBL4828251 | 0.86 | ADRB1 (0.87) | ADRB1SIGMAR1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964605-B2 | Phenyl piperazine compounds, pharmaceutical composition comprising the same, and use thereof | SK HOLDINGS CO., LTD. (KR) | 2011-06-21 | — | — | US | claimed |
| US-20090298851-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-12-03 | — | — | US | claimed |
| WO-2009145590-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | claimed |
| US-7964605-B2 | Phenyl piperazine compounds, pharmaceutical composition comprising the same, and use thereof | SK HOLDINGS CO., LTD. (KR) | 2011-06-21 | — | — | US | disclosed |
| US-20090298851-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-12-03 | — | — | US | disclosed |
| WO-2009145590-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298851-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND USE THEREOF | GRIK5, PLP2, PMP22 | ADRB1 1434/4885SIGMAR1 526/4885HTR3E 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.