Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL28214584 | 1.00 | — | — | |
| Guanidine SCHEMBL66977 | 1.00 | — | — | |
| Guanidine SCHEMBL20138497 | 1.00 | NOS2 (0.39) | — | |
| Guanidine SCHEMBL30875702 | 1.00 | NOS2 (0.39) | — | |
| Guanidine SCHEMBL27595748 | 0.94 | — | — | |
| Guanidine SCHEMBL9397537 | 0.94 | — | — | |
| Guanidine SCHEMBL28214616 | 0.94 | — | — | |
| Guanidine SCHEMBL15816733 | 0.94 | — | — | |
| Guanidine SCHEMBL7265251 | 0.94 | — | — | |
| Guanidine SCHEMBL28107159 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069622-A | Nitrite salts of 1, 1-metformin, pharmaceutical compositions and methods of use | 诺沃梅迪科斯有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116987014-A | Nitrite salts of 1, 1-metformin, pharmaceutical compositions and methods of use | 诺沃梅迪科斯有限公司 | 2023-11-03 | — | — | CN | disclosed |
| EP-1921051-B1 | Silica-based coating composition and its use for coating cement-bonded objects | LAFARGE SA (FR) | 2013-02-27 | — | — | EP | disclosed |
| US-8129461-B2 | Binder of amorphous silica and a vinyl functional silicone polymer, filler particles and water; weathering resistant, better adhesive properties, superior self cleaning properties | LAFARGE SA (FR) | 2012-03-06 | — | — | US | disclosed |
| US-20080261024-A1 | SILICA-BASED COATING COMPOSITION AND ITS USE FOR COATING CEMENT-BONDED OBJECTS | HOLCIM TECHNOLOGY LTD (CH) | 2008-10-23 | — | — | US | disclosed |
| EP-1921051-A1 | Silica-based coating composition and its use for coating cement-bonded objects | Lafarge SA (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-3895956-A | Water permeability reducing inorganic coating slurry composition | NISSAN CHEMICAL IND LTD | 1975-07-22 | — | — | US | disclosed |