Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274750 | 0.90 | CYP2D6 (0.49) | CYP2D6HTTKDM4EALDH1A1HPGD | |
| SCHEMBL27921144 | 0.85 | CYP2D6 (0.68) | CYP2D6HTTKDM4EALDH1A1HPGD | |
| SCHEMBL27902363 | 0.85 | CYP2D6 (0.68) | CYP2D6HTTKDM4EALDH1A1HPGD | |
| SCHEMBL17400300 | 0.85 | CYP2D6 (0.68) | CYP2D6HTTKDM4EALDH1A1HPGD | |
| SCHEMBL12891618 | 0.85 | CYP2D6 (0.68) | CYP2D6HTTKDM4EALDH1A1HPGD | |
| SCHEMBL8537338 | 0.83 | CYP2D6 (0.66) | CYP2D6HTTKDM4EALDH1A1HPGD | |
| SCHEMBL3103628 | 0.82 | KDM4E (0.51) | CYP2D6HTTKDM4EALDH1A1HPGD | |
| SCHEMBL17400293 | 0.80 | CYP2D6 (0.51) | CYP2D6HTTKDM4EALDH1A1HPGD | |
| SCHEMBL17400315 | 0.80 | CYP2D6 (0.59) | CYP2D6HTTKDM4EALDH1A1HPGD | |
| SCHEMBL21555486 | 0.79 | CYP2D6 (0.55) | CYP2D6HTTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202347-B2 | Compound, production method therefor, and use of said compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2019-02-12 | — | — | US | disclosed |
| US-20180093954-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202347-B2 | Compound, production method therefor, and use of said compound | PGC, CYP51A1, WEE1 | CYP2D6 898/4885HTT 1067/4885KDM4E 3499/4885 |
| US-20180093954-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | PGC, WEE1, CYP51A1 | CYP2D6 960/4885HTT 1699/4885KDM4E 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.