Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274465 | 0.81 | HTT (0.60) | CYP2D6HTTALDH1A1GAAKDM4E | |
| SCHEMBL13096663 | 0.80 | CYP2D6 (0.53) | CYP2D6HTTALDH1A1GAAKDM4E | |
| SCHEMBL20030409 | 0.80 | CYP2D6 (0.51) | CYP2D6HTTALDH1A1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL3097740 | 0.79 | CYP2D6 (0.52) | CYP2D6HTTALDH1A1GAAKDM4E | |
| SCHEMBL8024152 | 0.77 | CYP2D6 (0.51) | CYP2D6HTTALDH1A1GAAKDM4E | |
| SCHEMBL8537338 | 0.75 | CYP2D6 (0.66) | CYP2D6HTTALDH1A1GAAKDM4E | |
| SCHEMBL17400309 | 0.75 | CYP2D6 (0.49) | CYP2D6HTTALDH1A1GAAKDM4E | |
| SCHEMBL21555486 | 0.75 | CYP2D6 (0.55) | CYP2D6HTTALDH1A1GAAKDM4E | |
| SCHEMBL20274750 | 0.75 | CYP2D6 (0.49) | CYP2D6HTTALDH1A1GAAKDM4E | |
| SCHEMBL31514827 | 0.75 | KDM4E (0.46) | ALDH1A1GAAKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202347-B2 | Compound, production method therefor, and use of said compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2019-02-12 | — | — | US | disclosed |
| EP-3336080-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | Microbial Chemistry Research Foundation (JP) | 2018-06-20 | — | — | EP | disclosed |
| EP-3336081-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | Microbial Chemistry Research Foundation (JP) | 2018-06-20 | — | — | EP | disclosed |
| US-20180093954-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2018-04-05 | — | — | US | disclosed |
| US-20180093954-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2018-04-05 | — | — | US | disclosed |
| EP-2963020-B1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | MICROBIAL CHEM RES FOUND (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-9850211-B2 | Compound, production method therefor, and use of said compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-9850211-B2 | Compound, production method therefor, and use of said compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20170174631-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-06-22 | — | — | US | disclosed |
| US-20170174631-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-06-22 | — | — | US | disclosed |
| US-9617217-B2 | Compound, production method therefor, and use of said compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-04-11 | — | — | US | disclosed |
| US-9617217-B2 | Compound, production method therefor, and use of said compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2017-04-11 | — | — | US | disclosed |
| US-20160009651-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2016-01-14 | — | — | US | disclosed |
| US-20160009651-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2016-01-14 | — | — | US | disclosed |
| EP-2963020-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | Microbial Chemistry Research Foundation (JP) | 2016-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174631-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | CYP51A1, PGC, GGPS1 | CYP2D6 1320/4885HTT 2303/4885ALDH1A1 1465/4885 |
| US-20160009651-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | PGC, WEE1, CYP51A1 | CYP2D6 960/4885HTT 1699/4885ALDH1A1 2234/4885 |
| US-10202347-B2 | Compound, production method therefor, and use of said compound | PGC, CYP51A1, WEE1 | CYP2D6 898/4885HTT 1067/4885ALDH1A1 2334/4885 |
| US-20180093954-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND USE OF SAID COMPOUND | PGC, WEE1, CYP51A1 | CYP2D6 960/4885HTT 1699/4885ALDH1A1 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.