Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030950 | 0.92 | KDM4E (0.34) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL17547135 | 0.89 | KDM4E (0.35) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL20030473 | 0.87 | PTGDR2 (0.35) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL20031008 | 0.84 | KDM4E (0.35) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19905855 | 0.84 | KDM4E (0.39) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL20030463 | 0.84 | CYP3A4 (0.36) | — | |
| SCHEMBL22506256 | 0.84 | CYP3A4 (0.36) | — | |
| SCHEMBL19905960 | 0.84 | KDM4E (0.42) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL20030918 | 0.83 | KDM4E (0.39) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL20030913 | 0.83 | MCHR1 (0.33) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064080-A1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2018-04-05 | — | — | WO | disclosed |