Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030463 | 1.00 | CYP3A4 (0.36) | CYP3A4PSIP1 | |
| SCHEMBL22506483 | 0.93 | PSIP1 (0.38) | CYP3A4PSIP1 | |
| SCHEMBL20030917 | 0.93 | PSIP1 (0.38) | CYP3A4PSIP1 | |
| SCHEMBL22506462 | 0.92 | CYP3A4 (0.34) | CYP3A4PSIP1 | |
| SCHEMBL20030947 | 0.92 | CYP3A4 (0.34) | CYP3A4PSIP1 | |
| SCHEMBL22506280 | 0.91 | CYP3A4 (0.38) | CYP3A4PSIP1 | |
| SCHEMBL20030907 | 0.91 | CYP3A4 (0.38) | CYP3A4PSIP1 | |
| SCHEMBL15332316 | 0.90 | CYP3A4 (0.38) | CYP3A4PSIP1 | |
| SCHEMBL23100270 | 0.89 | CYP3A4 (0.36) | CYP3A4PSIP1 | |
| SCHEMBL20101367 | 0.89 | CYP3A4 (0.37) | CYP3A4PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800772-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2020-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800772-B2 | Therapeutic compounds | NQO1, HAVCR2, CCR5 | CYP3A4 182/4885PSIP1 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.