Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 11/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030908 | 0.83 | CHRM1 (0.42) | CHRM1PDE2APDE11A | |
| SCHEMBL23673051 | 0.80 | CHRM1 (0.53) | CHRM1PDE2APDE11ABRD4CNR2 | |
| SCHEMBL20030497 | 0.79 | CHRM1 (0.77) | CHRM1PDE2APDE11A | |
| SCHEMBL23672901 | 0.79 | CHRM1 (0.60) | CHRM1PDE2APDE11A | |
| SCHEMBL23695832 | 0.79 | CHRM1 (0.54) | CHRM1PDE2APDE11ABRD4 | |
| SCHEMBL20031033 | 0.79 | CHRM1 (0.60) | CHRM1PDE2APDE11A | |
| SCHEMBL19268090 | 0.76 | CHRM1 (0.48) | CHRM1PDE2APDE11A | |
| SCHEMBL23672857 | 0.75 | CHRM1 (0.56) | CHRM1PDE2APDE11A | |
| SCHEMBL23672567 | 0.75 | CHRM1 (0.56) | CHRM1PDE2APDE11A | |
| SCHEMBL23673004 | 0.75 | CHRM1 (0.56) | CHRM1PDE2APDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018063552-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIVERSITY (US) | 2018-04-05 | — | — | WO | disclosed |