Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031506 | 0.85 | RET (0.31) | — | |
| SCHEMBL20031502 | 0.80 | SMURF1 (0.37) | — | |
| SCHEMBL9957376 | 0.76 | NR1H4 (0.43) | NR1H4 | |
| SCHEMBL20853741 | 0.76 | NR1H4 (0.41) | NR1H4 | |
| SCHEMBL21435654 | 0.74 | NR1H4 (0.46) | NR1H4 | |
| SCHEMBL19899876 | 0.73 | NR1H4 (0.42) | NR1H4 | |
| SCHEMBL21456718 | 0.73 | NR1H4 (0.41) | NR1H4 | |
| SCHEMBL18949092 | 0.69 | RET (0.34) | — | |
| SCHEMBL16906034 | 0.69 | PKM (0.34) | — | |
| SCHEMBL17839830 | 0.66 | NR1H4 (0.47) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |