Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | USP1 | O94782 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12404673 | 0.79 | PPARA (0.46) | PPARAPCSK9AOC3USP1DRD2 | |
| SCHEMBL18123532 | 0.79 | AOC3 (0.40) | PPARAPCSK9AOC3USP1 | |
| SCHEMBL20969942 | 0.77 | PPARA (0.40) | PPARAPCSK9AOC3GABRA1GABRG2 | |
| SCHEMBL22230009 | 0.75 | PCSK9 (0.42) | PPARAPCSK9AOC3USP1DRD2 | |
| SCHEMBL822577 | 0.72 | NPC1 (0.47) | PPARAAOC3USP1DRD2 | |
| SCHEMBL20031407 | 0.72 | PPARA (0.36) | PPARAAOC3USP1 | |
| SCHEMBL26951887 | 0.72 | GRM5 (0.35) | — | |
| SCHEMBL21233202 | 0.71 | CYP11B2 (0.40) | PPARA | |
| SCHEMBL21408699 | 0.71 | PPARA (0.46) | PPARAPCSK9AOC3USP1DRD2 | |
| SCHEMBL2276295 | 0.69 | AOC3 (0.48) | PPARAPCSK9AOC3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093951-A1 | PESTICIDALLY ACTIVE CARBAMOYLATED AND THIOCARBAMOYLATED OXIME DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093951-A1 | PESTICIDALLY ACTIVE CARBAMOYLATED AND THIOCARBAMOYLATED OXIME DERIVATIVES | ACHE, DDT, BCHE | PPARA 1409/4885PCSK9 4439/4885AOC3 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.