Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031106 | 0.83 | RBP4 (0.54) | RBP4 | |
| SCHEMBL31014743 | 0.81 | NPC1 (0.40) | CD38HRH3 | |
| SCHEMBL24323742 | 0.80 | NPC1 (0.41) | HRH3 | |
| SCHEMBL2065518 | 0.79 | GPR119 (0.44) | RBP4OPRK1 | |
| SCHEMBL2065516 | 0.79 | GPR119 (0.44) | RBP4OPRK1 | |
| SCHEMBL31706833 | 0.75 | HTR2C (0.51) | — | |
| SCHEMBL31705963 | 0.75 | HTR2C (0.51) | — | |
| SCHEMBL24993524 | 0.75 | PIK3CA (0.44) | — | |
| SCHEMBL4566530 | 0.75 | HTR2C (0.51) | — | |
| SCHEMBL31705338 | 0.75 | PIK3CA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |