Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20027453 | 0.83 | MAPT (0.40) | MAOAMAOBLMNAGFERKMT2A | |
| SCHEMBL15756967 | 0.83 | MAOA (0.49) | MAOAMAOBKMT2ABRAFHDAC1 | |
| SCHEMBL20031601 | 0.83 | SCN9A (0.37) | MAOAMAOBLMNAGFERKMT2A | |
| SCHEMBL28526854 | 0.80 | POLB (0.50) | LMNAKMT2AL3MBTL1BRAFHDAC1 | |
| SCHEMBL16078374 | 0.80 | FLT1 (0.44) | KMT2AALDH1A1RAB9AHTR2A | |
| SCHEMBL22407099 | 0.79 | BRAF (0.41) | KMT2ABRAFHDAC1MAPTALDH1A1 | |
| SCHEMBL29741807 | 0.78 | AR (0.54) | MAOAMAOBKMT2ABRAFHDAC1 | |
| SCHEMBL10634442 | 0.77 | KDM4E (0.48) | KMT2AMAPTALDH1A1NPSR1RAB9A | |
| SCHEMBL16078417 | 0.77 | HTT (0.51) | LMNAKMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL6436949 | 0.76 | HTR2A (0.53) | MAOAMAOBLMNAGFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018060088-A1 | 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES AS FUNGICIIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |