Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031602 | 0.83 | MAOA (0.40) | SCN9ALMNAGFERKMT2AL3MBTL1 | |
| SCHEMBL15756967 | 0.76 | MAOA (0.49) | KMT2AMAOAMAOBBRAFHDAC1 | |
| SCHEMBL28526854 | 0.76 | POLB (0.50) | LMNAKMT2AL3MBTL1BRAFHDAC1 | |
| SCHEMBL22407099 | 0.75 | BRAF (0.41) | KMT2ABRAFHDAC1MMP1PPARG | |
| SCHEMBL15756626 | 0.75 | GSK3B (0.49) | LMNAL3MBTL1MAOAMAOBBRAF | |
| SCHEMBL20027454 | 0.73 | GSK3B (0.37) | LMNAGFERKMT2AL3MBTL1MAOA | |
| SCHEMBL29601876 | 0.73 | HTR2A (0.53) | SCN9ALMNAGFERKMT2AL3MBTL1 | |
| SCHEMBL6436949 | 0.73 | HTR2A (0.53) | SCN9ALMNAGFERKMT2AL3MBTL1 | |
| SCHEMBL22406874 | 0.72 | BRAF (0.43) | KMT2ABRAFHDAC1MMP1 | |
| SCHEMBL10599282 | 0.71 | HTR2A (0.54) | SCN9AKMT2AMAOAMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018060088-A1 | 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES AS FUNGICIIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |