Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 18/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP21A2 | P08686 | 9/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031604 | 0.90 | CYP3A4 (0.36) | CYP3A4THRBCYP21A2CYP19A1CYP17A1 | |
| SCHEMBL20031127 | 0.87 | FNTA (0.33) | SLC6A2HTR2ASLC6A4SLC6A3KCNH2 | |
| SCHEMBL21631894 | 0.83 | CYP3A4 (0.44) | CYP3A4THRBCYP21A2CYP19A1CYP17A1 | |
| SCHEMBL21632262 | 0.78 | CYP3A4 (0.38) | CYP3A4THRBCYP21A2CYP19A1CYP17A1 | |
| SCHEMBL21887073 | 0.75 | CYP3A4 (0.47) | CYP3A4THRBCYP21A2CYP19A1CYP17A1 | |
| SCHEMBL30611136 | 0.75 | CYP3A4 (0.47) | CYP3A4THRBCYP21A2CYP19A1CYP17A1 | |
| SCHEMBL20031605 | 0.74 | FNTA (0.32) | HTR2ASLC6A4KCNH2NPBWR1FNTA | |
| SCHEMBL21632114 | 0.74 | NPBWR1 (0.31) | HTR2ASLC6A4KCNH2NPBWR1FNTA | |
| SCHEMBL24061653 | 0.73 | HMOX1 (0.54) | CYP3A4CYP21A2CYP19A1CYP17A1CYP11B1 | |
| Difenoconazole SCHEMBL15932941 | 0.73 | CYP3A4 (0.68) | CYP3A4THRBCYP21A2CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200029563-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2020-01-30 | — | — | US | disclosed |
| WO-2018060088-A1 | 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES AS FUNGICIIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200029563-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES | PIP5K1B, PIP5K1A, PIP5K1C | CYP3A4 2019/4885THRB 3255/4885CYP21A2 4090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.