Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068346 | 1.00 | MEN1 (0.53) | MEN1KMT2ARAB9AGAACYP3A4 | |
| SCHEMBL1695820 | 0.87 | GPR35 (0.43) | MEN1KMT2ARAB9AGAACYP3A4 | |
| SCHEMBL5582440 | 0.87 | MEN1 (0.54) | MEN1KMT2ARAB9AGAACYP3A4 | |
| SCHEMBL5582439 | 0.87 | MEN1 (0.54) | MEN1KMT2ARAB9AGAACYP3A4 | |
| SCHEMBL5582438 | 0.87 | MEN1 (0.54) | MEN1KMT2ARAB9AGAACYP3A4 | |
| SCHEMBL6404329 | 0.85 | CYP1A2 (0.55) | MEN1KMT2ARAB9AGAACYP3A4 | |
| SCHEMBL28062163 | 0.85 | KMT2A (0.53) | MEN1KMT2ARAB9AGAACYP3A4 | |
| SCHEMBL6695015 | 0.85 | CYP1A2 (0.55) | MEN1KMT2ARAB9AGAACYP3A4 | |
| SCHEMBL6404322 | 0.85 | CYP1A2 (0.55) | MEN1KMT2ARAB9AGAACYP3A4 | |
| SCHEMBL6615905 | 0.84 | RAB9A (0.53) | MEN1KMT2ARAB9AGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530322-A4 | NOVEL AND IMPROVED METHOD FOR DETERMINATION OF E. COLI IN WATER | UNIV CALIFORNIA (US) | 1994-06-29 | — | — | EP | claimed |
| EP-0530322-A1 | NOVEL AND IMPROVED METHOD FOR DETERMINATION OF E. COLI IN WATER. | UNIV CALIFORNIA (US) | 1993-03-10 | — | — | EP | claimed |
| WO-1991018111-A1 | NOVEL AND IMPROVED METHOD FOR DETERMINATION OF E. COLI IN WATER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-11-28 | — | — | WO | claimed |
| US-7964709-B2 | Mutant tyrosine repressor, a gene encoding the same, and a method for producing L-DOPA | AJINOMOTO CO., INC. (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20090258400-A1 | Mutant Tyrosine Repressor, a Gene Encoding the Same, and a Method for Producing L-Dopa | KUMAGAI HIDEHIKO | 2009-10-15 | — | — | US | disclosed |
| US-7365161-B2 | Mutant tyrosine repressor which does not require tyrosine to induce expression of the tyrosine phenol-lyase gene | AJINOMOTO CO., INC. (JP) | 2008-04-29 | — | — | US | disclosed |
| EP-1582529-B1 | Mutant tyrosine repressor, a gene encoding the same, and a method for producing L-DOPA | AJINOMOTO KK (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-20050277174-A1 | Mutant tyrosine repressor, a gene encoding the same, and a method for producing L-DOPA | AJINOMOTO CO., INC. (JP) | 2005-12-15 | — | — | US | disclosed |
| EP-1582529-A1 | Mutant tyrosine repressor, a gene encoding the same, and a method for producing L-DOPA | Ajinomoto Co., Inc. (JP) | 2005-10-05 | — | — | EP | disclosed |
| EP-0733642-B1 | Benzazepin-, benzoxazepin- and benzothiazepin-N-acetic acid-derivatives, their preparation and their pharmaceutical compositions | SOLVAY PHARM GMBH (DE) | 2000-11-29 | — | — | EP | disclosed |
| US-5677297-A | ENZYME INHIBITOR FOR TREATING THE HEART FAILURE TO REDUCE THE CARDIAC PRESSURE, DIURETICS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5629202-A | FROM INDOLE, AMMONIUM CHLORIDE AND PYRUVIC ACID OR SODIUM PYRUVATE, CONTROLLED FEEDING OF REACTANTS BASED ON PREDEFINED PROFILE, ENZYMATIC REACTION | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1997-05-13 | — | — | US | disclosed |
| EP-0733642-A1 | Benzazepin-, benzoxazepin- and benzothiazepin-N-acetic acid-derivatives, their preparation and their pharmaceutical compositions | Kali-Chemie Pharma GmbH (DE) | 1996-09-25 | — | — | EP | disclosed |
| EP-0530322-A4 | NOVEL AND IMPROVED METHOD FOR DETERMINATION OF E. COLI IN WATER | UNIV CALIFORNIA (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0530322-A1 | NOVEL AND IMPROVED METHOD FOR DETERMINATION OF E. COLI IN WATER. | UNIV CALIFORNIA (US) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991018111-A1 | NOVEL AND IMPROVED METHOD FOR DETERMINATION OF E. COLI IN WATER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-11-28 | — | — | WO | disclosed |