Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21423155 | 0.84 | NOTUM (0.36) | CNR2CNR1KMT2A | |
| SCHEMBL17106362 | 0.83 | MAOB (0.42) | POLBMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11530777 | 0.81 | HPGD (0.45) | CNR2CNR1MAPTTP53RAB9A | |
| SCHEMBL11509018 | 0.80 | PTPRB (0.47) | — | |
| SCHEMBL5198639 | 0.79 | RIPK1 (0.45) | — | |
| SCHEMBL1249256 | 0.78 | CYP3A4 (0.33) | CNR2CNR1MAPTKMT2AMEN1 | |
| SCHEMBL20032507 | 0.77 | CYP4A11 (0.45) | CNR2CNR1 | |
| SCHEMBL20032506 | 0.77 | CYP4A11 (0.45) | CNR2CNR1 | |
| SCHEMBL11648125 | 0.76 | PTGS1 (0.44) | POLBMAPTKDM4ETP53RAB9A | |
| SCHEMBL563644 | 0.76 | PARP10 (0.42) | POLBPGK1PGK2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018060280-A1 | ENDOSOMOLYTIC AGENTS FOR GENE THERAPY | UCB BIOPHARMA SPRL (BE) | 2018-04-05 | — | — | WO | disclosed |