Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 4/20 | 0.52 |
| ▸ | WNT3A | P56704 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21231294 | 0.88 | CTNNB1 (0.56) | CTNNB1WNT3AKDM4EKMOKDM2B | |
| SCHEMBL16614192 | 0.88 | CTNNB1 (0.56) | CTNNB1WNT3AKDM4EKMOKDM2B | |
| SCHEMBL23024775 | 0.76 | CTNNB1 (0.68) | CTNNB1WNT3AKDM4EATMTSHR | |
| SCHEMBL31396077 | 0.76 | CTNNB1 (0.68) | CTNNB1WNT3AKDM4EATMTSHR | |
| SCHEMBL20032574 | 0.75 | CTNNB1 (0.51) | CTNNB1WNT3AKDM4EKMORAB9A | |
| SCHEMBL21382764 | 0.74 | CTNNB1 (0.58) | CTNNB1WNT3AKDM4ETSHRMAPT | |
| SCHEMBL997528 | 0.71 | CTNNB1 (0.58) | CTNNB1WNT3AKDM4EATMTSHR | |
| SCHEMBL15980041 | 0.70 | CTNNB1 (0.79) | CTNNB1WNT3ATSHRRAB9AHPGD | |
| SCHEMBL32670175 | 0.69 | CTNNB1 (0.46) | CTNNB1WNT3AKDM4EMAPTRAB9A | |
| SCHEMBL20032573 | 0.68 | TDP1 (0.63) | KDM4EKMOMAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938252-B2 | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof | CHDI FOUNDATION, INC. (US) | 2018-04-10 | — | — | US | disclosed |