Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17485689 | 0.95 | TDP1 (0.39) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL21254347 | 0.92 | POLB (0.36) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL22381392 | 0.92 | TDP1 (0.36) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL20032595 | 0.91 | POLB (0.39) | TDP1POLBAPEX1HTTSRD5A2 | |
| SCHEMBL23544524 | 0.90 | TDP1 (0.34) | TDP1POLBAPEX1HTTSRD5A2 | |
| SCHEMBL19881906 | 0.90 | TDP1 (0.34) | TDP1POLBAPEX1HTTSRD5A2 | |
| SCHEMBL24158065 | 0.90 | TDP1 (0.35) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL22072003 | 0.88 | POLB (0.39) | TDP1POLBAPEX1HTTSRD5A2 | |
| SCHEMBL22592364 | 0.88 | POLB (0.39) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL21891797 | 0.87 | POLB (0.36) | TDP1POLBAPEX1HTTSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938229-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9938229-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |