Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17485689 | 0.96 | TDP1 (0.39) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL21254347 | 0.93 | POLB (0.36) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL20032596 | 0.92 | TDP1 (0.36) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL22592364 | 0.91 | POLB (0.39) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL24158065 | 0.91 | TDP1 (0.35) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL23544524 | 0.89 | TDP1 (0.34) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL19881906 | 0.89 | TDP1 (0.34) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL22072003 | 0.89 | POLB (0.39) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL23919397 | 0.88 | POLB (0.37) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL21417786 | 0.87 | POLB (0.40) | TDP1POLBAPEX1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759997-B2 | Polymerizable compound, liquid crystal medium containing same and liquid crystal display device | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2020-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759997-B2 | Polymerizable compound, liquid crystal medium containing same and liquid crystal display device | BPHL, KLK3, NEFM | TDP1 2192/4885POLB 1544/4885APEX1 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.