SCHEMBL20032909

SCHEMBL20032909

CCC(/C=C\CO)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KISS1R Q969F8 1/20 0.32
CA2 P00918 1/20 0.31
MAPK1 P28482 1/20 0.31
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16445082 1.00 KISS1R (0.32) KISS1RCA2MAPK1CHRM1AKR1A1
SCHEMBL15228491 0.84 TP53 (0.30) MAPK1
SCHEMBL10946153 0.84 GRIK1 (0.37) CA2MAPK1CHRM1AKR1A1CHRM3
SCHEMBL1717440 0.84 GRIK1 (0.37) CA2MAPK1CHRM1AKR1A1CHRM3
SCHEMBL1717439 0.84 GRIK1 (0.37) CA2MAPK1CHRM1AKR1A1CHRM3
SCHEMBL16445194 0.83 CA1 (0.34) KISS1R
SCHEMBL11482990 0.80 ALDH1A1 (0.46) CA2MAPK1CHRM1AKR1A1CHRM3
SCHEMBL10997734 0.80 ALDH1A1 (0.31) CA2MAPK1CHRM1AKR1A1CHRM3
SCHEMBL10997745 0.80 ALDH1A1 (0.31) CA2MAPK1CHRM1AKR1A1CHRM3
SCHEMBL11482992 0.80 ALDH1A1 (0.46) CA2MAPK1CHRM1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938253-B2 Catalysts for efficient Z-selective metathesis TRUSTEES OF BOSTON COLLEGE (US) 2018-04-10 US disclosed