Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165466 | 0.83 | ALDH1A1 (0.44) | ALDH1A1NPSR1LMNAKMT2AMAPT | |
| SCHEMBL18843472 | 0.80 | ALDH1A1 (0.32) | ALDH1A1LMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2415072 | 0.79 | ALDH1A1 (0.42) | ALDH1A1NPSR1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL31214124 | 0.79 | ALDH1A1 (0.42) | ALDH1A1NPSR1LMNAKMT2AGAA | |
| SCHEMBL20033674 | 0.76 | ALDH1A1 (0.40) | ALDH1A1NPSR1LMNAGAASMN1; SMN2 | |
| SCHEMBL29504068 | 0.76 | TSHR (0.44) | ALDH1A1NPSR1MAPTGAASMN1; SMN2 | |
| SCHEMBL1747710 | 0.76 | TSHR (0.44) | ALDH1A1NPSR1MAPTGAASMN1; SMN2 | |
| SCHEMBL1141727 | 0.75 | ALDH1A1 (0.39) | ALDH1A1NPSR1LMNAMAPTGAA | |
| SCHEMBL120994 | 0.74 | ALDH1A1 (0.56) | ALDH1A1NPSR1LMNAMAPTGAA | |
| SCHEMBL29414916 | 0.74 | ALDH1A1 (0.56) | ALDH1A1NPSR1LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938236-B2 | Antiviral agents against HBV infection | DREXEL UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |