Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910775 | 0.83 | HSD11B1 (0.47) | HSD11B1TSHRALDH1A1NPSR1PTGS1 | |
| SCHEMBL13515230 | 0.75 | MAPK1 (0.46) | TSHRALDH1A1PTGS2NR4A3HIF1A | |
| SCHEMBL28288415 | 0.74 | HSD11B1 (0.54) | HSD11B1ALDH1A1NR4A3 | |
| SCHEMBL2890820 | 0.74 | HSD11B1 (0.60) | HSD11B1TSHRALDH1A1NPSR1 | |
| SCHEMBL14793221 | 0.73 | POLB (0.48) | TSHRALDH1A1NPSR1NR4A3HIF1A | |
| SCHEMBL15875209 | 0.71 | HSD11B1 (0.42) | HSD11B1TSHRPTGS1 | |
| SCHEMBL19158185 | 0.71 | TSHR (0.33) | TSHR | |
| SCHEMBL1500290 | 0.71 | TSHR (0.58) | HSD11B1TSHRALDH1A1PTGS1PTGS2 | |
| SCHEMBL23871900 | 0.69 | TSHR (0.32) | HSD11B1TSHR | |
| SCHEMBL13819946 | 0.68 | ALDH1A1 (0.49) | HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9941479-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |