Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19083664 | 0.89 | CNR1 (0.35) | CNR1TSHRALDH1A1HPGDMAPT | |
| SCHEMBL19083864 | 0.83 | MAPT (0.35) | CNR1TSHRALDH1A1HPGDMAPT | |
| SCHEMBL23768611 | 0.83 | ALDH1A1 (0.45) | TSHRALDH1A1ATMHPGDDNM1 | |
| SCHEMBL15281943 | 0.77 | ALDH1A1 (0.41) | TSHRALDH1A1ATMHPGDDNM1 | |
| SCHEMBL23196453 | 0.77 | DNM1 (0.45) | CNR1TSHRALDH1A1MAPTDNM1 | |
| SCHEMBL18643021 | 0.77 | DNM1 (0.45) | CNR1TSHRALDH1A1MAPTDNM1 | |
| SCHEMBL24769898 | 0.77 | MAPT (0.33) | HPGDMAPT | |
| SCHEMBL24241911 | 0.75 | CNR1 (0.33) | CNR1HPGD | |
| SCHEMBL20860759 | 0.75 | ALDH1A1 (0.40) | CNR1TSHRALDH1A1MAPT | |
| SCHEMBL951438 | 0.75 | ALDH1A1 (0.41) | CNR1ALDH1A1MAPTFAAHDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305784-A1 | HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS | Janssen Pharmaceutica NV (BE) | 2018-04-11 | — | — | EP | disclosed |