SCHEMBL20036854

SCHEMBL20036854

Cc1c(-c2ccc(F)cc2F)cc2c(c1-c1c(C)c(-c3ccc(F)cc3F)cc3ccccc13)=CCCC=2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.32
ADORA1 P30542 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12583243 0.85 GPR84 (0.40) GPR84ADORA1TRPA1
SCHEMBL12583259 0.72 MBNL1 (0.42) GPR84ADORA1
SCHEMBL14327778 0.67 CYP1A2 (0.35) GPR84
SCHEMBL12642413 0.67 GCGR (0.50)
SCHEMBL12583333 0.66 GPR84 (0.38) GPR84ADORA1TRPA1
SCHEMBL12583233 0.65 GPR84 (0.41) GPR84
SCHEMBL12583412 0.64 GCGR (0.34) GPR84TRPA1
SCHEMBL20036814 0.62 MC4R (0.35)
SCHEMBL20381924 0.62 GPR84 (0.40) GPR84
SCHEMBL12086034 0.62 CES1 (0.44) GPR84TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1712549-B1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME NAGASE & CO LTD (JP) 2018-04-11 EP disclosed