Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037281 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL20037309 | 0.81 | LMNA (0.77) | ALDH1A1KDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL20037206 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL9393409 | 0.78 | MAPT (0.60) | ALDH1A1KDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL20037297 | 0.77 | KLK6 (0.79) | ALDH1A1KDM4ERAB9AKMT2AKLK6 | |
| SCHEMBL6959086 | 0.74 | LMNA (0.58) | ALDH1A1KDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL20037308 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL9389469 | 0.74 | ALDH1A1 (0.62) | ALDH1A1KDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL31560024 | 0.74 | ALDH1A1 (0.61) | ALDH1A1KDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL3571881 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KDM4EHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305781-A1 | CHEMICAL SUBSTANCES WHICH INHIBIT THE ENZYMATIC ACTIVITY OF HUMAN KALLIKREIN-RELATED PEPTIDASE 6 (KLK6) | Deutsches Krebsforschungszentrum (DE) | 2018-04-11 | — | — | EP | disclosed |