Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | AKT2 | P31751 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15611245 | 0.84 | SLC6A3 (0.46) | LOXL2OPRM1OPRL1SLC6A3SLC6A4 | |
| SCHEMBL3356351 | 0.83 | ATM (0.42) | SLC6A3SLC6A2SLC6A4CYP2D6KCNH2 | |
| SCHEMBL19368539 | 0.83 | ABAT (0.41) | OPRL1SLC6A2TAAR1AKT2GSK3B | |
| SCHEMBL13540017 | 0.83 | CYP1A2 (0.38) | OPRM1SLC6A2SLC6A4KCNH2TAAR1 | |
| SCHEMBL1002871 | 0.83 | AKT2 (0.47) | SLC6A3SLC6A4TAAR1MAOBHTR2C | |
| SCHEMBL23083579 | 0.82 | MAOA (0.47) | LOXL2OPRM1OPRL1SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL4875338 | 0.81 | AKT2 (0.46) | SLC6A3SLC6A4TAAR1MAOBHTR2C | |
| Hydrochloric Acid SCHEMBL1003304 | 0.81 | AKT2 (0.46) | SLC6A3SLC6A4TAAR1MAOBHTR2C | |
| Hydrochloric Acid SCHEMBL23070913 | 0.81 | MAOA (0.46) | OPRM1OPRL1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL28787375 | 0.79 | SLC6A2 (0.37) | SLC6A3SLC6A2SLC6A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105219-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | INCYTE CORP (US) | 2018-04-11 | — | — | EP | disclosed |