Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20038238 | 0.90 | DRD3 (0.43) | DRD3KCNH2NPC1RAB9AL3MBTL1 | |
| SCHEMBL18291667 | 0.88 | DRD3 (0.48) | DRD3KCNH2NPC1RAB9AL3MBTL1 | |
| SCHEMBL20038232 | 0.86 | NPC1 (0.44) | NPC1RAB9AL3MBTL1GPR55NPSR1 | |
| SCHEMBL20249324 | 0.84 | NPC1 (0.42) | NPC1RAB9AL3MBTL1GPR55NPSR1 | |
| SCHEMBL20038327 | 0.82 | DRD3 (0.47) | DRD3KCNH2MAPTELANEMEN1 | |
| SCHEMBL20037537 | 0.80 | HRH3 (0.47) | DRD3KCNH2MAPTELANE | |
| SCHEMBL20037547 | 0.80 | DRD3 (0.43) | DRD3KCNH2ELANEKMT2A | |
| SCHEMBL20038205 | 0.79 | DRD3 (0.41) | DRD3KCNH2ELANEMEN1KMT2A | |
| SCHEMBL18291315 | 0.78 | DRD3 (0.41) | DRD3KCNH2ELANE | |
| SCHEMBL20037522 | 0.77 | NPC1 (0.35) | DRD3NPC1RAB9AL3MBTL1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |