Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | DCK | P27707 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20038458 | 0.81 | GFER (0.52) | GFERSMN1; SMN2ALDH1A1KDM4ETDP1 | |
| SCHEMBL20249398 | 0.80 | GFER (0.49) | GFERSMN1; SMN2ALDH1A1KDM4ETDP1 | |
| SCHEMBL18912708 | 0.78 | CYP1A2 (0.52) | SMN1; SMN2ALDH1A1KDM4EBPTF | |
| SCHEMBL26739775 | 0.76 | CYP1A2 (0.55) | SMN1; SMN2KDM4EBPTF | |
| SCHEMBL22489681 | 0.73 | PANK3 (0.58) | SMN1; SMN2MEN1KMT2ABPTFPANK3 | |
| SCHEMBL22489691 | 0.73 | PANK3 (0.59) | PANK3 | |
| SCHEMBL18291681 | 0.72 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL9210914 | 0.72 | RAB9A (0.60) | GFERSMN1; SMN2ALDH1A1KDM4ETDP1 | |
| SCHEMBL25590723 | 0.72 | KDM4E (0.47) | ALDH1A1KDM4EBPTF | |
| SCHEMBL20037716 | 0.71 | BPTF (0.44) | SMN1; SMN2KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |