Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND3 | P30281 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 2/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037820 | 0.81 | GRM2 (0.38) | GRM2ALDH1A1 | |
| SCHEMBL2233826 | 0.79 | GRM2 (0.38) | MTORGRM2ALDH1A1 | |
| SCHEMBL20255421 | 0.79 | GRM2 (0.38) | GRM2ALDH1A1 | |
| SCHEMBL18291601 | 0.79 | DRD2 (0.41) | MTORGRM2ALDH1A1PIK3CA | |
| SCHEMBL2233831 | 0.79 | DRD2 (0.41) | MTORGRM2ALDH1A1PIK3CA | |
| SCHEMBL20249172 | 0.77 | CCR9 (0.37) | GRM2ALDH1A1 | |
| SCHEMBL23768076 | 0.74 | HCAR3 (0.38) | ALDH1A1CYP11B1CYP11B2HCAR3CPB2 | |
| SCHEMBL17828163 | 0.72 | HRH3 (0.55) | ALDH1A1METTL3ACHE | |
| SCHEMBL171824 | 0.72 | KMT2A (0.43) | ALDH1A1 | |
| SCHEMBL27896110 | 0.71 | GRM2 (0.35) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |