Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21267595 | 0.89 | KDM4E (0.53) | KMT2AHRH3LTA4HICAM1ALDH1A1 | |
| SCHEMBL20203580 | 0.84 | ALDH1A1 (0.50) | KMT2AHRH3LTA4HALDH1A1MEN1 | |
| SCHEMBL18291546 | 0.83 | KMT2A (0.56) | S1PR5KMT2AL3MBTL1HRH3LTA4H | |
| SCHEMBL20203465 | 0.82 | HRH3 (0.50) | KMT2AHRH3LTA4HMEN1PTK2 | |
| SCHEMBL21267598 | 0.80 | MGAT2 (0.46) | KMT2AHRH3MEN1 | |
| SCHEMBL20037857 | 0.80 | L3MBTL1 (0.51) | S1PR5KMT2AL3MBTL1HRH3LTA4H | |
| SCHEMBL20249111 | 0.80 | S1PR5 (0.51) | S1PR5KMT2AL3MBTL1HRH3LTA4H | |
| SCHEMBL20037688 | 0.79 | PARP1 (0.42) | KMT2AHRH3ALDH1A1 | |
| SCHEMBL12028959 | 0.79 | HRH3 (0.47) | KMT2AHRH3ALDH1A1MEN1 | |
| SCHEMBL4547913 | 0.79 | HRH3 (0.50) | L3MBTL1HRH3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |