Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 4/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20255430 | 0.95 | HTR1B (0.44) | HTR1BHTR1DCHRNB2CHRNA4HRH1 | |
| SCHEMBL4591760 | 0.79 | NPC1 (0.39) | KDM4EALDH1A1LMNAGAATDP1 | |
| SCHEMBL256070 | 0.78 | ACACB (0.36) | KDM4EALDH1A1LMNAGAA | |
| SCHEMBL256104 | 0.78 | RAB9A (0.48) | KDM4EALDH1A1LMNA | |
| SCHEMBL18291293 | 0.77 | HTR1B (0.42) | HTR1BHTR1DCHRNB2CHRNA4HRH1 | |
| SCHEMBL20037638 | 0.76 | KDM4E (0.42) | HTR1BHTR1DCHRNB2CHRNA4HRH1 | |
| SCHEMBL20173484 | 0.76 | KDM4E (0.42) | HTR1BKDM4EGAA | |
| SCHEMBL3299644 | 0.75 | HTR7 (0.46) | HTR1BCHRNB2CHRNA4KDM4E | |
| SCHEMBL256106 | 0.75 | ACACB (0.41) | GAATDP1 | |
| SCHEMBL18291647 | 0.75 | HTR1B (0.46) | HTR1BHTR1DCHRNB2CHRNA4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |