Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821117 | 0.89 | KDM4E (0.68) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL5307853 | 0.89 | — | — | |
| SCHEMBL458012 | 0.89 | KDM4E (0.68) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL3624681 | 0.89 | KDM4E (0.68) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL23014621 | 0.82 | KDM4E (0.60) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL7748218 | 0.82 | KDM4E (0.60) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL8036117 | 0.80 | KDM4E (0.58) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL16731723 | 0.80 | KDM4E (0.58) | KDM4ETSHRPOLBPKMALDH1A1 | |
| SCHEMBL16656262 | 0.80 | HSD17B10 (0.52) | KDM4EALDH1A1GAASTAT6SMN1; SMN2 | |
| SCHEMBL13654249 | 0.80 | KDM4E (0.58) | KDM4ETSHRPOLBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |