SCHEMBL458012

SCHEMBL458012

NC(=O)CN1CCN(CC(N)=O)CCN(CC(N)=O)CCN(CC(N)=O)CC1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.68
TSHR P16473 2/20 0.50
POLB P06746 1/20 0.50
PKM P14618 1/20 0.50
ALDH1A1 P00352 5/20 0.47
L3MBTL1 Q9Y468 1/20 0.42
RAD52 P43351 1/20 0.42
STAT6 P42226 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2821117 1.00 KDM4E (0.68) KDM4ETSHRPOLBPKMALDH1A1
SCHEMBL3624681 1.00 KDM4E (0.68) KDM4ETSHRPOLBPKMALDH1A1
SCHEMBL5307853 1.00
SCHEMBL7748218 0.92 KDM4E (0.60) KDM4ETSHRPOLBPKMALDH1A1
SCHEMBL23014621 0.92 KDM4E (0.60) KDM4ETSHRPOLBPKMALDH1A1
SCHEMBL8036117 0.89 KDM4E (0.58) KDM4ETSHRPOLBPKMALDH1A1
SCHEMBL15043622 0.89 KDM4E (0.58) KDM4ETSHRPOLBPKMALDH1A1
SCHEMBL13654249 0.89 KDM4E (0.58) KDM4ETSHRPOLBPKMALDH1A1
SCHEMBL16731723 0.89 KDM4E (0.58) KDM4ETSHRPOLBPKMALDH1A1
SCHEMBL20038482 0.89 KDM4E (0.58) KDM4ETSHRPOLBPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1078 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094950-A Ligand compound with quinoline structure, and radioactive or non-radioactive marker and application thereof 2026-05-26 CN claimed
CN-122071508-A Targeting NPY polypeptide nuclide ligand and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2026-05-22 CN claimed
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US claimed
US-20260137821-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF C-BIOMEX CO., LTD. (KR) 2026-05-21 US claimed
WO-2026098519-A1 RADIOLIGAND COMPOUNDS AND USES THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2026-05-15 WO claimed
WO-2026101949-A1 COMPOUNDS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF RAYZEBIO, INC. (US) 2026-05-15 WO claimed
CN-122005879-A Modified GRPR antagonist peptides for cancer imaging and treatment 慕尼黑工业大学 2026-05-12 CN claimed
US-20260097139-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GnRHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-04-09 US claimed
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2026-03-26 US claimed
US-20260077071-A1 Targeted Delivery of Theranostic Agents PETER MACCALLUM CANCER INST (AU) 2026-03-19 US claimed
EP-3619191-A1 PHARMACOKINETIC ENHANCEMENTS OF BIFUNCTIONAL CHELATES AND USES THEREOF Fusion Pharmaceuticals Inc. (CA) 2020-03-11 EP claimed
US-20190083662-A1 IGF-1R MONOCLONAL ANTIBODIES AND USES THEREOF OXFORD FINANCE LLC 2019-03-21 US claimed
US-20190030194-A1 PHARMACOKINETIC ENHANCEMENTS OF BIFUNCTIONAL CHELATES AND USES THEREOF CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION (CA) 2019-01-31 US claimed
WO-2018204869-A1 PHARMACOKINETIC ENHANCEMENTS OF BIFUNCTIONAL CHELATES AND USES THEREOF Fusion Pharmaceuticals Inc. (CA) 2018-11-08 WO claimed
WO-2018204872-A2 IGF-1R MONOCLONAL ANTIBODIES AND USES THEREOF Fusion Pharmaceuticals Inc. (CA) 2018-11-08 WO claimed
EP-3294316-A2 RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R H. Lee Moffitt Cancer Center And Research Institute, Inc. (US) 2018-03-21 EP claimed
US-20170327520-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES SCV GMBH (DE) 2017-11-16 US claimed
WO-2016179529-A2 RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2016-11-10 WO claimed
US-9194802-B2 Luminescent probes having a phenanthridinyl antenna, and methods of use REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2015-11-24 US claimed
US-20140080163-A1 LUMINESCENT PROBES HAVING A PHENANTHRIDINYL ANTENNA, AND METHODS OF USE NATIONAL SCIENCE FOUNDATION 2014-03-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF KLK3, FOLH1, PSMA1 KDM4E 4115/4885TSHR 540/4885POLB 3628/4885
US-20260097139-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GnRHR) TARGETED THERAPEUTICS AND USES THEREOF GNRHR, GHRHR, FSHR KDM4E 1996/4885TSHR 28/4885POLB 2573/4885
US-20190030194-A1 PHARMACOKINETIC ENHANCEMENTS OF BIFUNCTIONAL CHELATES AND USES THEREOF SLC7A1, SLC19A1, PAICS KDM4E 2561/4885TSHR 892/4885POLB 3302/4885
US-20260077071-A1 Targeted Delivery of Theranostic Agents CCKAR, NPY1R, NPY2R KDM4E 3098/4885TSHR 117/4885POLB 1489/4885
US-20260137821-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF CA5A, CA1, CA9 KDM4E 1685/4885TSHR 1511/4885POLB 2094/4885
US-20170327520-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES PTH1R, VDR, MEN1 KDM4E 3345/4885TSHR 166/4885POLB 2042/4885
US-20190083662-A1 IGF-1R MONOCLONAL ANTIBODIES AND USES THEREOF IGF1R, IGFBP1, IGFBP2 KDM4E 3656/4885TSHR 36/4885POLB 4141/4885
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR KDM4E 2930/4885TSHR 5/4885POLB 2325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.