Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208756 | 1.00 | HSD17B10 (0.52) | HSD17B10SLC6A9KDM4EGLRA1OR51E2 | |
| Tetraxetan SCHEMBL3364489 | 0.87 | HSD17B10 (0.54) | HSD17B10SLC6A9KDM4EGLRA1OR51E2 | |
| Glycine SCHEMBL308073 | 0.87 | HSD17B10 (0.54) | HSD17B10SLC6A9KDM4EGLRA1OR51E2 | |
| Tetraxetan SCHEMBL2635294 | 0.87 | HSD17B10 (0.64) | HSD17B10SLC6A9KDM4ES1PR1ALDH1A1 | |
| SCHEMBL321989 | 0.87 | HSD17B10 (0.64) | HSD17B10SLC6A9KDM4ES1PR1ALDH1A1 | |
| Tetraxetan SCHEMBL2017956 | 0.87 | HSD17B10 (0.64) | HSD17B10SLC6A9KDM4ES1PR1ALDH1A1 | |
| SCHEMBL6848102 | 0.87 | HSD17B10 (0.64) | HSD17B10SLC6A9KDM4ES1PR1ALDH1A1 | |
| SCHEMBL173508 | 0.87 | HSD17B10 (0.64) | HSD17B10SLC6A9KDM4ES1PR1ALDH1A1 | |
| Tetraxetan SCHEMBL18018 | 0.87 | HSD17B10 (0.64) | HSD17B10SLC6A9KDM4ES1PR1ALDH1A1 | |
| SCHEMBL3503521 | 0.87 | HSD17B10 (0.64) | HSD17B10SLC6A9KDM4ES1PR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012604-B2 | Triazanonane derivatives or pharmaceutically acceptable salt thereof for enhanced fluorine-18 labeling | Snur & DB Foundation (KR) | 2015-04-21 | — | — | US | disclosed |