Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037777 | 0.90 | KMT2A (0.42) | MAPK1ATML3MBTL1 | |
| SCHEMBL20038497 | 0.85 | PDE2A (0.38) | PDE2AALDH1A1ATMNPSR1L3MBTL1 | |
| SCHEMBL20038582 | 0.84 | KMT2A (0.45) | ATML3MBTL1 | |
| SCHEMBL20038553 | 0.80 | ALDH1A1 (0.58) | MAPK1PDE2AALDH1A1NPSR1KDM4E | |
| SCHEMBL18291394 | 0.80 | ALDH1A1 (0.58) | MAPK1PDE2AALDH1A1NPSR1KDM4E | |
| SCHEMBL12049097 | 0.77 | CHRNB2 (0.51) | ALDH1A1ATMKDM4ECD274 | |
| SCHEMBL4554100 | 0.77 | CHRNB2 (0.56) | ALDH1A1L3MBTL1KDM4ECD274 | |
| SCHEMBL19230351 | 0.76 | CYP2D6 (0.60) | ALDH1A1KDM4E | |
| SCHEMBL20037831 | 0.76 | ALDH1A1 (0.54) | MAPK1ALDH1A1NPSR1KDM4EHTT | |
| SCHEMBL12334539 | 0.76 | HRH3 (0.59) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |