Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 7/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21414353 | 0.83 | CDK4 (0.37) | MAPTCYP3A4CYP2D6LMNAPDCD1 | |
| SCHEMBL21414409 | 0.81 | PNMT (0.44) | MAPTCYP3A4CYP2D6LMNAPDCD1 | |
| SCHEMBL18819902 | 0.81 | PDCD1 (0.52) | MAPTCYP3A4CYP2D6PDCD1CD274 | |
| SCHEMBL12693988 | 0.80 | CDK4 (0.43) | MAPTCYP3A4CYP2D6LMNAPDCD1 | |
| SCHEMBL18820431 | 0.79 | CDK4 (0.42) | MAPTCYP3A4CYP2D6LMNAPDCD1 | |
| SCHEMBL21452319 | 0.79 | CDK4 (0.42) | MAPTLMNAPDCD1CD274POLB | |
| SCHEMBL18291660 | 0.79 | CDK4 (0.44) | PDCD1CD274JAK2 | |
| SCHEMBL18819903 | 0.78 | CDK4 (0.42) | LMNAPDCD1CD274POLBFLT3 | |
| SCHEMBL18291672 | 0.76 | ADRA1B (0.45) | PDCD1CD274 | |
| SCHEMBL12706734 | 0.76 | CD274 (0.47) | MAPTPDCD1CD274POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |