Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 10/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20038664 | 0.84 | CA12 (0.50) | ALDH1A1MAPTRECQLHSD17B10TP53 | |
| SCHEMBL20038644 | 0.81 | NPC1 (0.55) | ALDH1A1MAPTTP53ALOX15 | |
| SCHEMBL20038659 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTAPPTSHRRECQL | |
| SCHEMBL4154037 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTAPPTSHRRECQL | |
| SCHEMBL11507985 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTAPPTSHRRECQL | |
| SCHEMBL153943 | 0.76 | TSHR (0.67) | ALDH1A1MAPTAPPTSHRRECQL | |
| SCHEMBL6971804 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTAPPTSHRRECQL | |
| SCHEMBL13295121 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTAPPTSHRRECQL | |
| SCHEMBL24140273 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTAPPTSHRRECQL | |
| SCHEMBL4636150 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTAPPTSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102637-B1 | METHOD FOR PURIFICATION OF ANTIBODIES, ANTIBODY FRAGMENTS OR ENGINEERED VARIANTS THEREOF USING SPECIFIC ANTHRAQUINONE DYE-LIGAND STRUCTURES | BASF SE (DE) | 2018-04-11 | — | — | EP | disclosed |