Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23918534 | 0.80 | KDM1A (0.52) | ALDH1A1MAPTIDO1PLK1TSHR | |
| SCHEMBL4154037 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTAPPTSHRMEN1 | |
| SCHEMBL11507985 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTAPPTSHRMEN1 | |
| SCHEMBL153943 | 0.78 | TSHR (0.67) | ALDH1A1MAPTAPPTSHRMEN1 | |
| SCHEMBL83839 | 0.78 | ALDH1A1 (0.58) | ALDH1A1IDO1PLK1MEN1KMT2A | |
| SCHEMBL1143678 | 0.76 | IDO1 (0.55) | ALDH1A1MAPTIDO1PLK1MEN1 | |
| SCHEMBL20038680 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTAPPIDO1TSHR | |
| SCHEMBL11815020 | 0.76 | IDO1 (0.50) | ALDH1A1MAPTIDO1PLK1MEN1 | |
| SCHEMBL27800216 | 0.76 | IDO1 (0.45) | ALDH1A1MAPTIDO1PLK1MEN1 | |
| SCHEMBL24140273 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTAPPTSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240350496-A1 | Design, Synthesis, and Structure-Activity Relationships of Substituted Pyrido[3,2-d]Pyrimidines as Microtubule Targeting Agents and Anti-Cancer Agents | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT | 2024-10-24 | — | — | US | disclosed |
| US-20240247142-A1 | NOVEL AMINE FUNCTIONALIZED POLYMERS AND METHODS OF PREPARATION | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-07-25 | — | — | US | disclosed |
| CN-117843633-A | Sulfoximine compounds, pharmaceutical compositions and uses thereof | 上海海和药物研究开发股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-115722266-B | Azacarbene-amino-ruthenium catalyst, and preparation method and application thereof | 广东药科大学 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023219521-A1 | NEW 2-(DIETHYLAMINO)-4,6-DIPHENYLBENZENE-1,3-CARBONITRILE DERIVATIVES, METHOD OF THEIR PRODUCTION, THEIR USE AND NEW PHOTOINITIATING SYSTEMS FOR PHOTOINITIATED CATIONIC, RADICAL, THIOL-ENE AND HYBRID POLYMERIZATION | Politechnika Krakowska im. Tadeusza Kościuszki (PL) | 2023-11-16 | — | — | WO | disclosed |
| CN-112585176-B | Novel amine-functionalized polymers and process for their preparation | 不列颠哥伦比亚大学 | 2023-10-24 | — | — | CN | disclosed |
| EP-3760662-B1 | POLYCARBONATE AND PREPARATION METHOD THEREOF | LG CHEMICAL LTD (KR) | 2023-10-04 | — | — | EP | disclosed |
| WO-2023156485-A1 | TRIARYLALKYL BORATE SALTS AS COINITIATORS IN NIR PHOTOPOLYMER COMPOSITIONS | COVESTRO DEUTSCHLAND AG (DE) | 2023-08-24 | — | — | WO | disclosed |
| CN-115722266-A | Novel aza-carbene-amido-ruthenium catalyst and preparation method and application thereof | 广东药科大学 | 2023-03-03 | — | — | CN | disclosed |
| US-11555107-B2 | Amine functionalized polymers and methods of preparation | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2023-01-17 | — | — | US | disclosed |
| EP-0169101-B1 | PROCESS FOR PREPARING (HYDROCARBYLTHIO)CYCLIC AMINES | ETHYL CORPORATION (US) | 1988-08-24 | — | — | EP | disclosed |
| US-4594453-A | Reacting hydrocarbyl disulfide with aromatic amine | ETHYL CORPORATION (US) | 1986-06-10 | — | — | US | disclosed |
| US-4585471-A | PREEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0169101-A1 | Process for preparing (hydrocarbylthio)cyclic amines | ETHYL CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |
| US-4549899-A | Hericidally active novel substituted 3-trihalogenomethyl-1,2,4-thiadiazol-5-yl-oxyacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-29 | — | — | US | disclosed |
| US-4540430-A | Herbicidally active novel substituted 3-trichloromethyl-1,2,4-thiadiazol-5-yl-oxyacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4500341-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| EP-0014880-B1 | PHENOXYCARBOXYLIC ACID AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |
| US-3982019-A | Insecticidal compositions containing trifluoromethyl ureas and method of controlling insects using said compositions | VELSICOL CHEMICAL CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240350496-A1 | Design, Synthesis, and Structure-Activity Relationships of Substituted Pyrido[3,2-d]Pyrimidines as Microtubule Targeting Agents and Anti-Cancer Agents | MAP2, TUBB6, TUBB1 | ALDH1A1 1800/4885MAPT 29/4885APP 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.