Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20039942 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 | |
| SCHEMBL17150940 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 | |
| SCHEMBL17690421 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 | |
| SCHEMBL18055936 | 0.88 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3TSHRCHRM2 | |
| SCHEMBL7849315 | 0.88 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3TSHRCHRM2 | |
| SCHEMBL18500925 | 0.85 | TSHR (0.54) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL18215079 | 0.82 | ACHE (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20039945 | 0.82 | ACHE (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12066159 | 0.82 | ACHE (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20039943 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091012-B1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | CENTREXION THERAPEUTICS CORP (US) | 2018-04-11 | — | — | EP | disclosed |