Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784599 | 0.98 | HSD17B3 (0.51) | KMT2ANPC1HSD17B3L3MBTL1ALDH1A1 | |
| SCHEMBL2743316 | 0.97 | NPC1 (0.57) | KMT2ANPC1HSD17B3L3MBTL1ALDH1A1 | |
| SCHEMBL10749473 | 0.89 | KMT2A (0.61) | KMT2ANPC1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL1360326 | 0.87 | HTR7 (0.65) | KMT2ANPC1HSD17B3L3MBTL1ALDH1A1 | |
| SCHEMBL10950721 | 0.87 | KMT2A (0.54) | KMT2ANPC1HSD17B3L3MBTL1ALDH1A1 | |
| SCHEMBL9442288 | 0.87 | CA12 (0.54) | KMT2ANPC1HSD17B3L3MBTL1ALDH1A1 | |
| SCHEMBL5147538 | 0.86 | L3MBTL1 (0.63) | KMT2ANPC1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL7460876 | 0.85 | KMT2A (0.53) | KMT2ANPC1HSD17B3L3MBTL1ALDH1A1 | |
| SCHEMBL7457718 | 0.85 | KMT2A (0.53) | KMT2ANPC1HSD17B3L3MBTL1ALDH1A1 | |
| SCHEMBL9308927 | 0.85 | PDE4B (0.62) | KMT2ANPC1L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091012-B1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | CENTREXION THERAPEUTICS CORP (US) | 2018-04-11 | — | — | EP | disclosed |