SCHEMBL20040137

SCHEMBL20040137

N#CC(C#N)=C1/C(=C(/N)I)S(=O)(=O)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
CHEK1 O14757 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21097473 0.85 GPR3 (0.39) GPR3MEN1KMT2AALDH1A1MAPT
SCHEMBL8636862 0.81 GPR3 (0.56) GPR3MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13193926 0.75 GPR3 (0.44) GPR3MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL20365633 0.75 GPR3 (0.40) GPR3MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL21311513 0.72 TDP2 (0.35) MEN1KMT2AALDH1A1MAPTGAA
SCHEMBL26361785 0.72 GPR3 (0.40) GPR3MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL13679292 0.72 GPR3 (0.40) GPR3MEN1KMT2AALDH1A1MAPT
SCHEMBL15146693 0.72 GPR3 (0.40) GPR3MEN1KMT2AALDH1A1MAPT
SCHEMBL14067692 0.70 GPR3 (0.42) GPR3MEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL19917208 0.69 TDP2 (0.50) MEN1KMT2AALDH1A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3306690-A1 ORGANIC SEMICONDUCTING COMPOUNDS Merck Patent GmbH (DE) 2018-04-11 EP disclosed