Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286358 | 1.00 | — | — | |
| SCHEMBL580308 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9334893 | 0.97 | — | — | |
| SCHEMBL6141 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL8303248 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL11313740 | 0.93 | — | — | |
| SCHEMBL3200905 | 0.89 | — | — | |
| SCHEMBL7353993 | 0.87 | — | — | |
| SCHEMBL10698992 | 0.84 | LMNA (0.35) | HRH3MEN1KMT2ALMNAL3MBTL1 | |
| Urea SCHEMBL7781133 | 0.82 | L3MBTL1 (0.50) | MEN1KMT2ALMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053923-B1 | TRIAZOLOPYRAZINE DERIVATIVES AS TYROSIN KINASE INHIBITORS | KOREA RES INST CHEMICAL TECH (KR) | 2018-04-11 | — | — | EP | disclosed |