Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17716128 | 0.93 | MAPK1 (0.55) | MAPK1HTTTSHRPOLBNR1H2 | |
| SCHEMBL17993378 | 0.90 | MAPK1 (0.54) | MAPK1HTTTSHRPOLBNR1H2 | |
| SCHEMBL22592972 | 0.85 | MAPK1 (0.55) | MAPK1HTTTSHRPOLBNR1H2 | |
| SCHEMBL17993421 | 0.85 | KDM4E (0.41) | MAPK1HTTALDH1A1KDM4EMAPT | |
| SCHEMBL822745 | 0.85 | ESR1 (0.54) | MAPK1HTTPOLBALDH1A1KDM4E | |
| SCHEMBL20040426 | 0.84 | MAPK1 (0.74) | MAPK1HTTTSHRPOLBNR1H2 | |
| SCHEMBL17993396 | 0.84 | KDM4E (0.37) | MAPK1HTTPOLBALDH1A1KDM4E | |
| SCHEMBL17723973 | 0.84 | MAPK1 (0.69) | MAPK1HTTTSHRPOLBNR1H2 | |
| SCHEMBL280035 | 0.84 | ESR1 (0.47) | ALDH1A1KDM4ETP53 | |
| SCHEMBL20040464 | 0.83 | MAPK1 (0.68) | MAPK1HTTTSHRPOLBNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053918-B1 | 2-carbazole substituted benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |