Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17993366 | 0.92 | MAPK1 (0.66) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20040426 | 0.90 | MAPK1 (0.74) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20040464 | 0.88 | MAPK1 (0.68) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30951244 | 0.86 | KDM4E (0.53) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15371684 | 0.85 | ESR1 (0.58) | MAPK1HTTALDH1A1KDM4EATM | |
| SCHEMBL20040409 | 0.84 | MAPK1 (0.54) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29466048 | 0.83 | KDM4E (0.50) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL540947 | 0.83 | MAPK1 (1.00) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28705086 | 0.83 | KDM4E (0.50) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17993382 | 0.83 | KDM4E (0.50) | MAPK1HTTALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053918-B1 | 2-carbazole substituted benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016067261-A1 | 5-((BENZ)IMIDAZOL-2-YL)BENZIMIDAZO[1,2-A]BENZIMIDAZOLES FOR ELECTRONIC APPLICATIONS | IDEMITSU KOSAN CO., LTD. (JP) | 2016-05-06 | — | — | WO | disclosed |