Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20040419 | 0.85 | TSHR (0.66) | TSHRMAPTTP53KDM4ESMN1; SMN2 | |
| SCHEMBL15631604 | 0.82 | TSHR (0.71) | TSHRMAPTTP53KDM4ETHRB | |
| SCHEMBL19721186 | 0.79 | TSHR (0.50) | TSHRMAPTTP53KDM4ETHRB | |
| SCHEMBL17570830 | 0.74 | TSHR (0.55) | TSHRMAPTTP53NPC1RAB9A | |
| SCHEMBL15605425 | 0.74 | TSHR (0.68) | TSHRMAPTTP53KDM4EHPGD | |
| SCHEMBL22513715 | 0.72 | HSD17B10 (0.42) | TSHRMAPTTP53KDM4ESMN1; SMN2 | |
| SCHEMBL19486457 | 0.71 | NPSR1 (0.49) | TSHRKDM4ESMN1; SMN2LCKKMT2A | |
| SCHEMBL17059040 | 0.70 | MPI (0.47) | MAPTKDM4ETHRBGAAL3MBTL1 | |
| SCHEMBL7850067 | 0.69 | RAB9A (0.62) | TSHRMAPTTP53KDM4ESMN1; SMN2 | |
| SCHEMBL22522687 | 0.69 | TSHR (0.51) | TSHRMAPTTP53KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178864-A1 | SEVEN-MEMBERED RING COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2017-10-19 | — | — | WO | disclosed |