Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404598 | 0.74 | ADRA2A (0.51) | ADRA2AKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL30636720 | 0.74 | ADRA2A (0.51) | ADRA2AKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL17361522 | 0.67 | CD274 (0.35) | ADRA2ACA12CA9KDM4ENPC1 | |
| SCHEMBL14552635 | 0.67 | MAOB (0.49) | CA12CA9KDM4ENPC1RAB9A | |
| SCHEMBL12257033 | 0.65 | ALOX5 (0.58) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL8988345 | 0.65 | MAPT (0.67) | CA12CA9KDM4ENPC1ALDH1A1 | |
| SCHEMBL23005350 | 0.65 | CYP3A4 (0.42) | ADRA2AKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL30545231 | 0.65 | FABP6 (0.42) | ADRA2AKDM4EALDH1A1MAPTPGR | |
| SCHEMBL26835590 | 0.65 | ADRA2A (0.52) | ADRA2ANPC1MAPTRAB9ACYP19A1 | |
| SCHEMBL5209759 | 0.65 | MAOB (0.41) | CA12CA9KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053918-B1 | 2-carbazole substituted benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |