Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 5/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.49 |
| ▸ | KIF11 | P52732 | 10/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685725 | 0.79 | ESR1 (0.48) | ESR1ESR2HDAC6 | |
| SCHEMBL2949294 | 0.79 | S1PR1 (0.49) | ESR1ESR2 | |
| SCHEMBL5682858 | 0.79 | ESR1 (0.61) | ESR1ESR2HDAC3HDAC4HDAC1 | |
| SCHEMBL14504042 | 0.78 | ESR1 (0.74) | ESR1ESR2HDAC3HDAC4HDAC1 | |
| SCHEMBL9977515 | 0.75 | ESR1 (0.61) | ESR1ESR2HDAC3HDAC4HDAC1 | |
| SCHEMBL20040655 | 0.75 | ESR1 (0.54) | ESR1ESR2HDAC3HDAC4HDAC1 | |
| SCHEMBL5682837 | 0.75 | ESR1 (0.53) | ESR1ESR2HDAC3HDAC4HDAC1 | |
| SCHEMBL764426 | 0.74 | CYP11B2 (0.53) | CYP11B2CYP11B1KIF11 | |
| SCHEMBL5685590 | 0.73 | CYP1A1 (0.47) | ESR1ESR2HDAC3HDAC4HDAC1 | |
| SCHEMBL10530572 | 0.72 | APP (0.62) | ESR1ESR2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305774-B1 | BENZOTHIOPHENE-CONTAINING LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2020-08-26 | — | — | EP | disclosed |
| US-10563126-B2 | Liquid crystal compound having benzothiophene, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20180127652-A1 | LIQUID CRYSTAL COMPOUND HAVING BENZOTHIOPHENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
| US-20180127652-A1 | LIQUID CRYSTAL COMPOUND HAVING BENZOTHIOPHENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
| EP-3305774-A1 | BENZOTHIOPHENE-CONTAINING LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-04-11 | — | — | EP | disclosed |