SCHEMBL764426

SCHEMBL764426

Cc1ccc(C(F)(F)F)c(F)c1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 5/20 0.53
CYP11B1 P15538 4/20 0.53
KIF11 P52732 12/20 0.48
KDM1A O60341 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14640087 0.84 KIF11 (0.42) CYP11B2CYP11B1KIF11
SCHEMBL10996601 0.82 KIF11 (0.41) CYP11B2CYP11B1KIF11
SCHEMBL168982 0.81 MPL (0.44) CYP11B2CYP11B1
SCHEMBL441485 0.81 KIF11 (0.44) CYP11B2CYP11B1KIF11
SCHEMBL4273522 0.80 SMN1; SMN2 (0.45) CYP11B2CYP11B1KIF11
SCHEMBL31490900 0.79 KIF11 (0.42) CYP11B2CYP11B1KIF11
SCHEMBL14195930 0.79 PDE3B (0.51) CYP11B2CYP11B1
SCHEMBL15385002 0.78 AR (0.58) CYP11B2CYP11B1KIF11
SCHEMBL144686 0.78 TP53 (0.42) CYP11B2CYP11B1KIF11
SCHEMBL11962356 0.77 KIF11 (0.41) CYP11B2CYP11B1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 630 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417531-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2024-12-19 US claimed
EP-4419603-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2024-08-28 EP claimed
CN-118437610-A Corrosion-resistant low-carbon steel pipe and preparation method thereof 淮安市逸臣精密机械有限公司 2024-08-06 CN claimed
CN-114665677-B Insulation treatment method for motor working under water 贵州航天林泉电机有限公司 2023-09-05 CN claimed
WO-2023067111-A1 METHOD FOR PRODUCING SELF-HEALING ORGANIC-INORGANIC MATERIALS ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN NANOCIENCIAS "CIC nanoGUNE" (ES) 2023-04-27 WO claimed
CN-115727064-A Electrically insulating bearing ring, method for producing an electrically insulating bearing ring and bearing 舍弗勒技术股份两合公司 2023-03-03 CN claimed
CN-110769945-B Cosmetic care film comprising a water-soluble layer and a vapor-deposited coating 宝洁公司 2023-01-24 CN claimed
CN-114665677-A Insulation processing method for underwater working motor 贵州航天林泉电机有限公司 2022-06-24 CN claimed
CN-114106304-A Low-temperature curing weather-resistant polyester resin, low-temperature curing weather-resistant powder coating and preparation method 安徽神剑新材料股份有限公司 2022-03-01 CN claimed
CN-112592471-B High-heat-resistance high-toughness polyester, polyester product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2021-05-07 CN claimed
US-20120149699-A1 IMIDAZO[1,2-a]PYRIDINE SULFONAMIDES AS TRPM8 MODULATORS JANSSEN PHARMACEUTICA, NV (BE) 2012-06-14 US claimed
US-8153682-B2 Sulfonamides as TRPM8 modulators JANSSEN PHARMACEUTICA, NV (BE) 2012-04-10 US claimed
EP-2183239-A1 SULFONAMIDES AS TRPM8 MODULATORS Janssen Pharmaceutica, N.V. (BE) 2010-05-12 EP claimed
US-20090264474-A1 SULFONAMIDES AS TRPM8 MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2009-10-22 US claimed
WO-2009012430-A1 SULFONAMIDES AS TRPM8 MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2009-01-22 WO claimed
CN-1978413-A TFPX synthesis method YUANXIN SCI & TECH MATERIAL CO (CN) 2007-06-13 CN claimed
CN-1978412-A Method for converting TCPX into TFPX YUANXINSCI & TECH MATERIAL CO (CN) 2007-06-13 CN claimed
EP-0113185-B2 SELECTIVE BROMINATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-07-24 EP claimed
EP-0113185-B1 SELECTIVE BROMINATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-09 EP claimed
EP-0113185-A1 Selective bromination process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-07-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149699-A1 IMIDAZO[1,2-a]PYRIDINE SULFONAMIDES AS TRPM8 MODULATORS TRPM8, TRPV1, TRPM2 CYP11B2 3606/4885CYP11B1 3773/4885KIF11 3126/4885
US-20090264474-A1 SULFONAMIDES AS TRPM8 MODULATORS TRPM8, TRPM5, TRPM2 CYP11B2 4010/4885CYP11B1 4156/4885KIF11 3345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.