Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.55 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 13/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546977 | 0.88 | SLC22A12 (0.56) | SLC22A12TAS2R14CNR2AR | |
| SCHEMBL10155141 | 0.83 | SLC22A12 (0.51) | SLC22A12TAS2R14ARTRPA1 | |
| SCHEMBL14919155 | 0.80 | SLC22A12 (0.55) | SLC22A12TAS2R14CNR2ARTRPA1 | |
| SCHEMBL8210097 | 0.79 | SLC22A12 (0.54) | SLC22A12TAS2R14ARTRPA1 | |
| SCHEMBL2973749 | 0.79 | AR (0.54) | SLC22A12TAS2R14ARTRPA1 | |
| SCHEMBL20179096 | 0.79 | SLC22A12 (0.54) | SLC22A12TAS2R14ARTRPA1 | |
| SCHEMBL17658051 | 0.79 | BLM (0.63) | SLC22A12TAS2R14AR | |
| SCHEMBL8410428 | 0.78 | ALDH1A1 (0.44) | SLC22A12 | |
| Hydrochloric Acid SCHEMBL552509 | 0.78 | SLC22A12 (0.52) | SLC22A12TAS2R14ARTRPA1 | |
| SCHEMBL5247689 | 0.78 | TAS2R14 (0.60) | SLC22A12TAS2R14AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243373-A1 | SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2020-12-03 | — | — | WO | disclosed |
| EP-2864289-B1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CB THERAPEUTICS INC (KY) | 2018-04-11 | — | — | EP | disclosed |